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Dana R. Crawford, PhD

Associate Professor
Immunology and Microbial Disease

Areas of Study

Redox, gene expression, and diet research

Education

  • Harvard UniversityPostdoctoral research
  • University of Massachusetts Medical CenterPostdoctoral research
  • Dartmouth CollegePhD
  • University of Massachusetts BostonBS/BA/MS

Research

Dr. Crawford's laboratory is primarily involved in redox, gene expression, and diet research. He has identified a number of genes (e.g., RCAN1 and mitochondrial polynucleotides) that are modulated by oxidative stress and is characterizing their function and possible clinical use in stress-related disorders. Most recently, this has focused on the involvement of mitochondrial RNA and DNA (both native and oxidized) in inflammation.

The laboratory is also involved in diet and nutrition as a healthy, low-cost, and translational approach to treating multiple disorders, a project we call dietary rational gene targeting. This novel approach uses healthy dietary agents to modulate key disorder-causing genes and proteins back toward the normal, in turn providing potential complementary and alternative treatment therapies. These studies include our creation of a new online dietary app (鈥淓at4Genes鈥) in collaboration with Rensselaer Polytechnic Institute.

Dr. Crawford also chairs the Capital Region Cancer Research (CRCR) group, an inter-institutional organization devoted to the cure of cancer.

Publications

Lin HY, Ramos RB, Crawford DR. Redox Rep. 2025 Dec;30(1):2491845. doi: 10.1080/13510002.2025.2491845. Epub 2025 Apr 17. PubMed PMID: 40247667; PubMed Central PMCID: PMC12010657.

Ford ML, Cooley JM, Sripada V, Xu Z, Erickson JS, Bennett KP,聽Crawford DR. 聽 Front Nutr. 2023 May 26;10:1196520. doi: 10.3389/fnut.2023.1196520. eCollection 2023.PMID:聽37305078

Crawford DR.聽Cureus.聽2021 Dec;13(12):e20205.聽doi: 10.7759/cureus.20205.聽eCollection 2021 Dec.聽PubMed PMID: 35004025; PubMed Central PMCID: PMC8729821.

Bagyi J, Sripada V, Aidone AM, Lin HY, Ruder EH, Crawford DR.聽Free Radic Biol Med.聽2021 Sep;173:19-28.聽doi: 10.1016/j.freeradbiomed.2021.07.021.聽Epub 2021 Jul 15.聽Review.聽PubMed PMID: 34274490.

Saxena AR, Ilic Z, Sripada V, Crawford DR.聽Nutr Res.聽2020 Jun;78:93-104.聽doi: 10.1016/j.nutres.2020.05.007.聽Epub 2020 May 19.聽PubMed PMID: 32563955.

Ilic Z, Saxena AR, Periasamy S, Crawford DR.聽Free Radic Biol Med.聽2019 Nov 1;143:62-69.聽doi: 10.1016/j.freeradbiomed.2019.07.019.聽Epub 2019 Jul 19.聽PubMed PMID: 31330178.

Saxena AR, Gao LY, Srivatsa S, Bobersky EZ, Periasamy S, Hunt DT, Altman KE, Crawford DR.聽Free Radic Biol Med.聽2017 Mar;104:371-379.聽doi: 10.1016/j.freeradbiomed.2017.02.009.聽Epub 2017 Feb 4.聽PubMed PMID: 28179110.

on the National Institute of Health's PubMed website.

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